Age-associated chronic diseases require age-old medicine Role of chronic inflammation/
Sahdeo Prasad; Bokyung Sung; Bharat B. Aggarwal
- Document electrònic
Most chronic diseases—such as cancer, cardiovascular disease (CVD), Alzheimer disease, Parkinson disease, arthritis, diabetes and obesity—are becoming leading causes of disability and death all over the world. lack of physical activity, poor nutrition, tobacco use, and excessive alcohol consumption. All the risk factors linked to these chronic diseases have been shown to up-regulate inflammation. Therefore, downregulation of inflammationassociated risk factors could prevent or delay these age-associated diseases. Althoughmodern science has developed several drugs for treating chronic diseases, most of these drugs are enormously expensive and are associated with serious side effects and morbidity. In this review, we present evidence on how chronic inflammation leads to ageassociated chronic disease. Furthermore,we discuss diet and lifestyle as solutions for age-associated chronic disease.